I have seen a few report of problems unique to the 8 gig Pi 4, which were to have been fixed by an update, USB error much like yours reported in October.
This post links to a 2020-11-23 fix fo the Pi 4.
Your patchbox is up to date?
(If there was just a brute force method to hide 4 gigs to see if the problem vanishes on a smaller Pi)