I’ve just tested a Hifiberry DACplusADCpro now on RPi4 with patchbox. It works. Can go down to 64-frame buffers with jack.
There were clicks every few seconds, though I followed the instructions in DACplusADCpro click noise – HiFiBerry which said to add the line “dtoverlay=hifiberry-dacplusadcpro,slave” to config.txt, and after I appended that line to the bottom of /boot/config.txt and reboot, the click sound went away.